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Levent Akyürek

Professor

Levent Akyürek
Professor
Akademisk grad: Docent,
levent.akyurek@gu.se
031-786 3456

Rumsnummer: 4376
Postadress: Box 440, 40530 Göteborg
Besöksadress: Medicinaregatan 9A , 41390 Göteborg


Avd för medicinsk kemi och cellbiologi vid Institutionen för biomedicin (Mer information)
Box 440
40530 Göteborg
Fax: 0 31-41 61 08

Besöksadress: Medicinaregatan 9 a-b , 40530 Göteborg

Om Levent Akyürek

Levent Akyürek is a vascular biologist in the field of angiogenesis during cardiovascular remodeling and tumor growth. Akyürek's early work defined the cellular interactions that stimulate the vasculoproliferative responses during transplant vasculopathy. These studies have indicated the important cellular determinants of neointima formation. Later, he examined neointimal smooth muscle and endothelial cell biology, both by inhibiting cellular proliferation using adenoviral gene therapy and by studying genes linked to cell cycle control.

His research activity has recently become focused on the involvement of filamins, a group of cytoskeleton proteins, in vascular cell signaling and transcription during the progression of cardiovascular and tumor diseases. Generation of filamin-deficient mouse models as well as mouse models to study the biological role of filamins during the progression of tumor growth and cardiovascular remodeling have been produced for the first time in his laboratory.

Dr. Akyürek graduated from the Medical School, Dokuz Eylül University, Turkey in 1989, and then completed his PhD program at Uppsala University in 1996. He worked as a postdoctoral fellow in the laboratory of Elizabeth G. Nabel at the University of Michigan and the National Institutes of Health, USA between 1997 and 2002. Dr. Akyürek became an Associate Professor of Cell Biology in 2004 and Professor in Pathology in 2014 at the University of Gothenburg. He currently acts as a reviewer on the editorial boards of several scientific journals in the field of vascular biology, transplantation immunology and molecular biology. He is also serving as clinical pathologist with expertise in molecular pathology at the Sahlgrenska Academy Hospital in Gothenburg.

Utvalda publikationer

Hypoxia-induced and calpain-dependent cleavage of filamin-A regulates the hypoxic response.
Xiaowei Zheng, Alex-Xianghua Zhou, Pegah Rouhi, Hidetaka Uramoto, Jan Borén et al.
Proceedings of the National Academy of Science of the United States of America, 2014

Senaste publikationer

Emergency thoracotomy in a Swedish setting: A consecutive series of 45 patients from a Scandinavian trauma hospital
Joel Beck, Hans Granhed, Levent Akyürek, David Pazooki
Journal of Trauma and Treatment, Artikel i vetenskaplig tidskrift 2016
Artikel i vetenskaplig tidskrift

Deficiency of filamin A in endothelial cells impairs left ventricular remodeling after myocardial infarction.
Sashidar Bandaru, Julia Grönros, Björn Redfors, Cağlar Cil, David Pazooki et al.
Cardiovascular research, Artikel i vetenskaplig tidskrift 2015
Artikel i vetenskaplig tidskrift

p110alpha hot spot mutations E545K and H1047R exert metabolic reprogramming independently of p110alpha kinase activity
Aditi Chaudhari, Daniel Krumlinde, Annika Lundqvist, Levent Akyürek, Sashidar Bandaru et al.
Molecular and Cellular Biology, Artikel i vetenskaplig tidskrift 2015
Artikel i vetenskaplig tidskrift

Antioxidants can increase melanoma metastasis in mice.
Kristell Le Gal, Mohamed X Ibrahim, Clotilde Wiel, Volkan I. Sayin, Murali K Akula et al.
Science translational medicine, Artikel i vetenskaplig tidskrift 2015
Artikel i vetenskaplig tidskrift

Amanuensprogram lockar forskarintresserade i Göteborg.
Levent Akyürek, Fredrik Hessulf, Ka-Wei Tang, Eric Hanse, Catharina Lindholm
Läkartidningen, Artikel i övriga tidskrifter 2014
Artikel i övriga tidskrifter

The Risk-Associated Long Noncoding RNA NBAT-1 Controls Neuroblastoma Progression by Regulating Cell Proliferation and Neuronal Differentiation.
Gaurav Kumar Pandey, Sanhita Mitra, Santhilal Subhash, Falk Hertwig, Meena Kanduri et al.
Cancer Cell, Artikel i vetenskaplig tidskrift 2014
Artikel i vetenskaplig tidskrift

Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A
Sashidar Bandaru, Xianghua Zhou, Pegah Rouhi, Yan Zhang, Martin Bergö et al.
Oncogenesis, Artikel i vetenskaplig tidskrift 2014
Artikel i vetenskaplig tidskrift

Hypoxia-induced and calpain-dependent cleavage of filamin-A regulates the hypoxic response.
Xiaowei Zheng, Alex-Xianghua Zhou, Pegah Rouhi, Hidetaka Uramoto, Jan Borén et al.
Proceedings of the National Academy of Science of the United States of America, Artikel i vetenskaplig tidskrift 2014
Artikel i vetenskaplig tidskrift

Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice
Rajesh K. Nallapalli, Mohamed X Ibrahim, Xianghua Zhou, Sashidar Bandaru, Sai Naresh Sunkara et al.
Molecular Cancer, Artikel i vetenskaplig tidskrift 2012
Artikel i vetenskaplig tidskrift

Utvalda publikationer

Hypoxia-induced and calpain-dependent cleavage of filamin-A regulates the hypoxic response.
Xiaowei Zheng, Alex-Xianghua Zhou, Pegah Rouhi, Hidetaka Uramoto, Jan Borén et al.
Proceedings of the National Academy of Science of the United States of America, 2014

Visar 1 - 10 av 28

2016

Emergency thoracotomy in a Swedish setting: A consecutive series of 45 patients from a Scandinavian trauma hospital
Joel Beck, Hans Granhed, Levent Akyürek, David Pazooki
Journal of Trauma and Treatment, Artikel i vetenskaplig tidskrift 2016
Artikel i vetenskaplig tidskrift

2015

Deficiency of filamin A in endothelial cells impairs left ventricular remodeling after myocardial infarction.
Sashidar Bandaru, Julia Grönros, Björn Redfors, Cağlar Cil, David Pazooki et al.
Cardiovascular research, Artikel i vetenskaplig tidskrift 2015
Artikel i vetenskaplig tidskrift

p110alpha hot spot mutations E545K and H1047R exert metabolic reprogramming independently of p110alpha kinase activity
Aditi Chaudhari, Daniel Krumlinde, Annika Lundqvist, Levent Akyürek, Sashidar Bandaru et al.
Molecular and Cellular Biology, Artikel i vetenskaplig tidskrift 2015
Artikel i vetenskaplig tidskrift

Antioxidants can increase melanoma metastasis in mice.
Kristell Le Gal, Mohamed X Ibrahim, Clotilde Wiel, Volkan I. Sayin, Murali K Akula et al.
Science translational medicine, Artikel i vetenskaplig tidskrift 2015
Artikel i vetenskaplig tidskrift

2014

Amanuensprogram lockar forskarintresserade i Göteborg.
Levent Akyürek, Fredrik Hessulf, Ka-Wei Tang, Eric Hanse, Catharina Lindholm
Läkartidningen, Artikel i övriga tidskrifter 2014
Artikel i övriga tidskrifter

The Risk-Associated Long Noncoding RNA NBAT-1 Controls Neuroblastoma Progression by Regulating Cell Proliferation and Neuronal Differentiation.
Gaurav Kumar Pandey, Sanhita Mitra, Santhilal Subhash, Falk Hertwig, Meena Kanduri et al.
Cancer Cell, Artikel i vetenskaplig tidskrift 2014
Artikel i vetenskaplig tidskrift

Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A
Sashidar Bandaru, Xianghua Zhou, Pegah Rouhi, Yan Zhang, Martin Bergö et al.
Oncogenesis, Artikel i vetenskaplig tidskrift 2014
Artikel i vetenskaplig tidskrift

Hypoxia-induced and calpain-dependent cleavage of filamin-A regulates the hypoxic response.
Xiaowei Zheng, Alex-Xianghua Zhou, Pegah Rouhi, Hidetaka Uramoto, Jan Borén et al.
Proceedings of the National Academy of Science of the United States of America, Artikel i vetenskaplig tidskrift 2014
Artikel i vetenskaplig tidskrift

2012

Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice
Rajesh K. Nallapalli, Mohamed X Ibrahim, Xianghua Zhou, Sashidar Bandaru, Sai Naresh Sunkara et al.
Molecular Cancer, Artikel i vetenskaplig tidskrift 2012
Artikel i vetenskaplig tidskrift

Visar 1 - 10 av 28

Sidansvarig: Cecilia Koskinen|Sidan uppdaterades: 2015-10-19
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