Organization of DNA in mammalian mitochondria
G. É R. Farge, Maria Falkenberg
International Journal of Molecular Sciences, Journal article 2019
Journal article

Structural basis for adPEO-causing mutations in the mitochondrial TWINKLE helicase.
Bradley Peter, Geraldine Farge, Carlos Pardo-Hernandez, Stefan Tångefjord, Maria Falkenberg
Human molecular genetics, Journal article 2019
Journal article

RNase H1 directs origin-specific initiation of DNA replication in human mitochondria
Viktor Posse, Ali Al-Behadili, Jay Uhler, Anders R Clausen, A. Reyes et al.
Plos Genetics, Journal article 2019
Journal article

Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions
Örjan Persson, Yazh Muthukumar, Swaraj Basu, Louise Jenninger, Jay Uhler et al.
Nature Communications, Journal article 2019
Journal article

Mitochondrial DNA replication in mammalian cells: overview of the pathway
Maria Falkenberg
Essays in Biochemistry, Review article 2018
Review article

A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL
Ali Al-Behadili, Jay Uhler, Anna-Karin Berglund, Bradley Peter, M. Doimo et al.
Nucleic acids research, Journal article 2018
Journal article

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria
S. Matic, M. Jiang, Thomas J. Nicholls, Jay Uhler, C. Dirksen-Schwanenland et al.
Nature Communications, Journal article 2018
Journal article

Defective mitochondrial protease LonP1 can cause classical mitochondrial disease
Bradley Peter, C. L. Waddington, M. Olahova, E. W. Sommerville, S. Hopton et al.
Human Molecular Genetics, Journal article 2018
Journal article

Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA
Thomas J. Nicholls, C. A. Nadalutti, E. Motori, E. W. Sommerville, G. S. Gorman et al.
Molecular Cell, Journal article 2018
Journal article

A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma
Triinu Siibak, P. Clemente, A. Bratic, H. Bruhn, T. E. S. Kauppila et al.
Human Molecular Genetics, Journal article 2017
Journal article

Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro.
Dmitry Litonin, Marina Sologub, Yonghong Shi, Maria Savkina, Michael Anikin et al.
The Journal of biological chemistry, Journal article 2010
Journal article

Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription
Christoph Freyer, Chan Bae Park, Mats I. Ekstrand, Yonghong Shi, Julia Khvorostova et al.
NUCLEIC ACIDS RESEARCH, Journal article 2010
Journal article

G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation
Paulina Wanrooij, Jay Uhler, Tomas Simonsson, Maria Falkenberg, Claes M Gustafsson
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Journal article 2010
Journal article

The human mitochondrial replication fork in health and disease.
Sjoerd Wanrooij, Maria Falkenberg
Biochimica et biophysica acta, Review article 2010
Review article

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication.
Javier Miralles Fusté, Sjoerd Wanrooij, Elisabeth Jemt, Caroline E Granycome, Tricia J Cluett et al.
Molecular cell, Journal article 2010
Journal article

Structure-function defects of the twinkle amino-terminal region in progressive external ophthalmoplegia.
Teresa Holmlund, Géraldine Farge, Vineet Pande, Jenny Korhonen, L Nilsson et al.
Biochimica et biophysica acta, Journal article 2009
Journal article

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging.
Joost van Mameren, Peter Gross, Geraldine Farge, Pleuni Hooijman, Mauro Modesti et al.
Proceedings of the National Academy of Sciences of the United States of America, Journal article 2009
Journal article

Structure casts light on mtDNA replication.
Maria Falkenberg, Nils-Göran Larsson
Cell, Magazine article 2009
Magazine article

The N-terminal domain of TWINKLE contributes to single-stranded DNA binding and DNA helicase activities.
Géraldine Farge, Teresa Holmlund, Julia Khvorostova, Reza Rofougaran, Anders Hofer et al.
Nucleic acids research, Journal article 2008
Journal article

Structure-function defects of the TWINKLE linker region in progressive external ophthalmoplegia.
Jenny A Korhonen, Vineet Pande, Teresa Holmlund, Géraldine Farge, Xuan Hoi Pham et al.
Journal of molecular biology, Journal article 2008
Journal article