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Maria Falkenberg


Maria Falkenberg
+46 31 786 3444

Room number: 5374
Postal Address: Box 440, 40530 Göteborg
Visiting Address: Medicinaregatan 9A , 41390 Göteborg

Department of Medical Biochemistry and Cell biology at Institute of Biomedicine (More Information)
Box 440
405 30 Göteborg
Fax: +46 31416108
Visiting Address: Medicinaregatan 9 A-B , 413 90 Göteborg

Latest publications

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria
Thomas J. Nicholls, H. Spahr, S. Jiang, S. J. Siira, C. Koolmeister et al.
Molecular Cell, Journal article 2019
Journal article

Organization of DNA in mammalian mitochondria
G. É R. Farge, Maria Falkenberg
International Journal of Molecular Sciences, Journal article 2019
Journal article

Structural basis for adPEO-causing mutations in the mitochondrial TWINKLE helicase.
Bradley Peter, Geraldine Farge, Carlos Pardo-Hernandez, Stefan Tångefjord, Maria Falkenberg
Human molecular genetics, Journal article 2019
Journal article

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria
S. Matic, M. Jiang, Thomas J. Nicholls, Jay Uhler, C. Dirksen-Schwanenland et al.
Nature Communications, Journal article 2018
Journal article

Defective mitochondrial protease LonP1 can cause classical mitochondrial disease
Bradley Peter, C. L. Waddington, M. Olahova, E. W. Sommerville, S. Hopton et al.
Human Molecular Genetics, Journal article 2018
Journal article

Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA
Thomas J. Nicholls, C. A. Nadalutti, E. Motori, E. W. Sommerville, G. S. Gorman et al.
Molecular Cell, Journal article 2018
Journal article

Showing 41 - 50 of 70


Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA
C Kukat, CA Wurm, H Spahr, Maria Falkenberg, NG Larsson et al.
Journal article


Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro.
Dmitry Litonin, Marina Sologub, Yonghong Shi, Maria Savkina, Michael Anikin et al.
The Journal of biological chemistry, Journal article 2010
Journal article

Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription
Christoph Freyer, Chan Bae Park, Mats I. Ekstrand, Yonghong Shi, Julia Khvorostova et al.
NUCLEIC ACIDS RESEARCH, Journal article 2010
Journal article

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication.
Javier Miralles Fusté, Sjoerd Wanrooij, Elisabeth Jemt, Caroline E Granycome, Tricia J Cluett et al.
Molecular cell, Journal article 2010
Journal article


Structure-function defects of the twinkle amino-terminal region in progressive external ophthalmoplegia.
Teresa Holmlund, Géraldine Farge, Vineet Pande, Jenny Korhonen, L Nilsson et al.
Biochimica et biophysica acta, Journal article 2009
Journal article

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging.
Joost van Mameren, Peter Gross, Geraldine Farge, Pleuni Hooijman, Mauro Modesti et al.
Proceedings of the National Academy of Sciences of the United States of America, Journal article 2009
Journal article

Structure casts light on mtDNA replication.
Maria Falkenberg, Nils-Göran Larsson
Cell, Magazine article 2009
Magazine article


The N-terminal domain of TWINKLE contributes to single-stranded DNA binding and DNA helicase activities.
Géraldine Farge, Teresa Holmlund, Julia Khvorostova, Reza Rofougaran, Anders Hofer et al.
Nucleic acids research, Journal article 2008
Journal article

Showing 41 - 50 of 70

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