An oral alpha-galactosylceramide adjuvanted Helicobacter pylori vaccine induces protective IL-1R-and IL-17R-dependent Th1 responses
S. Longet, A. Abautret-Daly, C. J. H. Davitt, C. P. McEntee, V. Aversa et al.
Npj Vaccines, Journal article 2019
Journal article

Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice
A. A. A. Pind, M. Dubik, S. Thorsdottir, A. Meinke, A. M. Harandi et al.
Frontiers in Immunology, Journal article 2019
Journal article

Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines
C. J. H. Davitt, S. Longet, A. Albutti, V. Aversa, Stefan Nordqvist et al.
Mucosal Immunology, Journal article 2019
Journal article

Proteomic analysis of cholera toxin adjuvant-stimulated human monocytes identifies Thrombospondin-1 and Integrin-beta 1 as strongly upregulated molecules involved in adjuvant activity
Manuela Terrinoni, Jan Holmgren, Michael Lebens, Maximilian Larena
Scientific Reports, Journal article 2019
Journal article

Requirement for Cyclic AMP/Protein Kinase A-Dependent Canonical NF kappa B Signaling in the Adjuvant Action of Cholera Toxin and Its Non-toxic Derivative mmCT
Manuela Terrinoni, Jan Holmgren, Michael Lebens, Maximilian Larena
Frontiers in Immunology, Journal article 2019
Journal article

B cells treated with CTB-p210 acquire a regulatory phenotype in vitro and reduce atherosclerosis in apolipoprotein E deficient mice
S. Rattik, P. T. Mantani, I. Y. Mattisson, I. Ljungcrantz, L. Sundius et al.
Vascular Pharmacology, Journal article 2018
Journal article

Preclinical immunogenicity and protective efficacy of an oral Helicobacter pylori inactivated whole cell vaccine and multiple mutant cholera toxin: A novel and non-toxic mucosal adjuvant
Jan Holmgren, Stefan Nordqvist, Margareta Blomquist, Frida Jeverstam, Michael Lebens et al.
Vaccine, Journal article 2018
Journal article

A Novel Nonantibiotic, lgt-Based Selection System for Stable Maintenance of Expression Vectors in Escherichia coli and Vibrio cholerae
Manuela Terrinoni, Stefan Nordqvist, Susanne Källgård, Jan Holmgren, Michael Lebens
Applied and Environmental Microbiology, Journal article 2018
Journal article

Cholera
John D. Clemens, G. Balakrish Nair, Tahmeed Ahmed, Firdausi Qadri, Jan Holmgren
The Lancet, Review article 2017
Review article

Deficiency in calcium-binding protein S100A4 impairs the adjuvant action of cholera toxin
Jiabin Sun, Jan Holmgren, Maximilian Larena, Manuela Terrinoni, Yu Fang et al.
Frontiers in Immunology, Journal article 2017
Journal article

Cholera toxin induces a transient depletion of CD8+ intraepithelial lymphocytes in the rat small intestine as detected by microarray and immunohistochemistry.
Carl-Fredrik Flach, Stefan Lange, Eva Jennische, Ivar Lönnroth, Jan Holmgren
Infection and immunity, Journal article 2005
Journal article

Mucosal immunity and vaccine design.
Cecil Czerkinsky, Ali M Harandi, Jan Holmgren
Edited book 2005
Edited book

Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea
Joaquin Sanchez, Jan Holmgren
CURRENT OPINION IN IMMUNOLOGY, Review article 2005
Review article

Mucosal immunity and vaccines
Jan Holmgren, Cecil Czerkinsky
Nature Medicine, Review article 2005
Review article

CpG oligodeoxynucleotide augments HSV-2 glycoprotein D DNA vaccine efficacy to generate T helper 1 response and subsequent protection against primary genital herpes infection in mice.
Sara Tengvall, Agnetha Josefsson, Jan Holmgren, Ali M Harandi
Journal of reproductive immunology, Journal article 2005
Journal article

Development of pathogenicity-driven definitions of outcomes for a field trial of a killed oral vaccine against enterotoxigenic Escherichia coli in Egypt: application of an evidence-based method
John Clemens, Stephen Savarino, Remon Abu-Elyazeed, Mohammad Safwat, Malla Rao et al.
J Infect Dis, Journal article 2004
Journal article

Antigen-specific in vitro suppression of murine Helicobacter pylori-reactive immunopathological T cells by CD4(+)CD25(+) regulatory T cells
Sukanya Raghavan, E. Suri-Payer, Jan Holmgren
Scandinavian Journal of Immunology, Journal article 2004
Journal article

In vivo adjuvant-induced mobilization and maturation of gut dendritic cells after oral administration of cholera toxin
Fabienne Anjuère, Carmelo Luci, Michael Lebens, Déborah Rousseau, Catherine Hervouet et al.
Journal of Immunology, Journal article 2004
Journal article

Coupling of antigen to cholera toxin for dendritic cell vaccination promotes the induction of MHC class I-restricted cytotoxic T cells and the rejection of a cognate antigen-expressing model tumor.
Kristina Eriksson, Jia-Bin Sun, Inger Nordström, Margareta Fredriksson, Marianne Lindblad et al.
European journal of immunology, Journal article 2004
Journal article

Expression of cholera toxin under non-AKI conditions in Vibrio cholerae El Tor induced by increasing the exposed surface of cultures
Joaquín Sánchez, Gerardo Medina, Thomas Buhse, Jan Holmgren, Gloria Soberón-Chavez
JOURNAL OF BACTERIOLOGY, Journal article 2004
Journal article