Anetta Härtlova

Adipose tissue macrophage dysfunction is associated with a breach of vascular integrity in

Markus Boesch, Andreas Lindhorst, Rita Feio-Azevedo, Paola Brescia, Alessandra Silvestri, Matthias Lannoo, Ellen Deleus, Joris Jaekers, Halit Topal, Baki Topal, Tessa Ostyn, Marie Wallays, Lena Smets, Lukas Van Melkebeke, Anetta Härtlova, Tania Roskams, Pierre Bedossa, Jef Verbeek, Olivier Govaere, Sven Francque, Alejandro Sifrim, Thierry Voet, Maria Rescigno, Martin Gericke, Hannelie Korf, Schalk van der Merwe
Journal of Hepatology - 2024

Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein

P.

Maria Schwarz, Caroline E Meyer, Alina Löser, Kristina Lossow, Julian Hackler, Christiane Ott, Susanne Jäger, Isabelle Mohr, Ella A Eklund, Angana A. H. Patel, Nadia Gul, Samantha Alvarez, Ilayda Altinonder, Clotilde Wiel, Maria Maares, Hajo Haase, Anetta Härtlova, Tilman Grune, Matthias B Schulze, Tanja Schwerdtle, Uta Merle, Hans Zischka, Volkan I. Sayin, Lutz Schomburg, Anna P Kipp
Nature communications - 2023

Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular

collagen

Ivo Fabrik, Orsolya Bilkei-Gorzo, Maria Öberg, Daniela Fabrikova, Johannes Fuchs, Carina Sihlbom, M. Goransson, Anetta Härtlova
Life Science Alliance (LSA) - 2023

Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer

retina

M. Kurzawa-Akanbi, P. Whitfield, F. Burte, P. M. Bertelli, V. Pathak, M. Doherty, B. Hilgen, L. Gliaudelyte, M. Platt, R. Queen, J. Coxhead, A. Porter, Maria Öberg, Daniela Fabrikova, T. Davey, C. S. Beh, M. Georgiou, J. Collin, V. Boczonadi, Anetta Härtlova, M. Taggart, J. Al-Aama, V. I. Korolchuk, C. M. Morris, J. Guduric-Fuchs, D. H. Steel, R. J. Medina, L. Armstrong, M. Lako
Journal of Extracellular Vesicles - 2022

The E3 ubiquitin ligase RNF115 regulates phagosome maturation and host response to bacterial

infection

Orsolya Bilkei-Gorzo, T. Heunis, J. L. Marin-Rubio, F. R. Cianfanelli, B. B. A. Raymond, J. Inns, Daniela Fabrikova, J. Peltier, F. Oakley, R. Schmid, Anetta Härtlova, M. Trost
EMBO Journal - 2022

The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I

axis

S. F. Erttmann, P. Swacha, K. M. Aung, B. Brindefalk, H. Jiang, Anetta Härtlova, B. E. Uhlin, S. N. Wai, N. O. Gekara
Immunity - 2022

MEFV and NLRP3 Inflammasome Expression Is Attributed to Immature Macrophages and Correlates with Serum Inflammatory Proteins in Crohn ' s Disease

Patients

Frida Gorreja, Charles Caër, Stephen T.A Rush, Sophia K. Forsskål, Anetta Härtlova, Maria K Magnusson, Elinor Bexe-Lindskog, Lars Börjesson, Mattias Block, Mary Jo Wick
Inflammation - 2022

Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body

disorders

M. Kurzawa-Akanbi, S. Tammireddy, Ivo Fabrik, M. K. Doherty, R. Heap, Björn Marcus Burmann, Irena Matečko-Burmann, M. Trost, J. M. Lucocq, A. V. Gherman, G. Fairfoul, P. Singh, F. Burte, A. Green, I. G. McKeith, P. D. Whitfield, Anetta Härtlova, C. M. Morris
Acta Neuropathologica - 2021

Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During

Remission

Lujain Maasfeh, Anetta Härtlova, Stefan Isaksson, Johanna Sundin, G. Mavroudis, O. Savolainen, H. Strid, Lena Öhman, Maria K Magnusson
Cellular and Molecular Gastroenterology and Hepatology - 2021

TPL-2 kinase induces phagosome acidification to promote macrophage killing of

bacteria

F. Breyer, Anetta Härtlova, T. Thurston, H. R. Flynn, P. Chakravarty, J. Janzen, J. Peltier, T. Heunis, A. P. Snijders, M. Trost, S. C. Ley
Embo Journal - 2021

The role of innate immunity and inflammation in Parkinson ' s

disease

Maria Öberg, Ivo Fabrik, Daniela Fabrikova, Nina Zehetner, Anetta Härtlova
Scandinavian Journal of Immunology - 2021

Simvastatin therapy attenuates memory deficits that associate with brain monocyte infiltration in chronic

hypercholesterolemia

Nicholas Don-Doncow, Lotte Vanherle, Frank Matthes, Sine Kragh Petersen, Hana Matuskova, Sara Rattik, Anetta Härtlova, Anja Meissner
npj Aging and Mechanisms of Disease - 2021

Macrophages and scavenger receptors in obesity-associated non-alcoholic liver fatty disease

(NAFLD)

Sine Kragh Petersen, Orsolya Bilkei-Gorzo, O. Govaere, Anetta Härtlova
Scandinavian Journal of Immunology - 2020

Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated

macrophages.

Manman Guo, Anetta Härtlova, Marek Gierliński, Alan Prescott, Josep Castellvi, Javier Hernandez Losa, Sine Kragh Petersen, Ulf Alexander Wenzel, Brian D Dill, Christoph H Emmerich, Santiago Ramon Y Cajal, David G Russell, Matthias Trost
The EMBO journal - 2019

Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS

Stimulation.

Anne-Marie Pauwels, Anetta Härtlova, Julien Peltier, Yasmine Driege, Griet Baudelet, Priscille Brodin, Matthias Trost, Rudi Beyaert, Eik Hoffmann
Molecular & cellular proteomics : MCP - 2019

Regulation of phagosome functions by post-translational modifications: a new

paradigm.

Paul Dean, Tiaan Heunis, Anetta Härtlova, Matthias Trost
Current opinion in chemical biology - 2019

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in

macrophages.

Anetta Härtlova, Susanne Herbst, Julien Peltier, Angela Rodgers, Orsolya Bilkei-Gorzo, Antony Fearns, Brian D Dill, Heyne Lee, Rowan Flynn, Sally A Cowley, Paul Davies, Patrick A Lewis, Ian G Ganley, Jennifer Martinez, Dario R Alessi, Alastair D Reith, Matthias Trost, Maximiliano G Gutierrez
The EMBO journal - 2018

Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor

palbociclib.

Teemu P Miettinen, Julien Peltier, Anetta Härtlova, Marek Gierliński, Valerie M Jansen, Matthias Trost, Mikael Björklund
The EMBO journal - 2018

Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate

Immunity.

Saskia F Erttmann, Anetta Härtlova, Marta Sloniecka, Faizal A M Raffi, Ava Hosseinzadeh, Tomas Edgren, Reza Rofougaran, Ulrike Resch, Maria Fällman, Torben Ek, Nelson O Gekara
Immunity - 2017

Subversion of innate immune responses by Francisella involves the disruption of TRAF3 and TRAF6 signalling

complexes.

Daniela Putzova, Swarupa Panda, Anetta Härtlova, Jiří Stulík, Nelson O Gekara
Cellular microbiology - 2017

Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome

Maturation.

Anetta Härtlova, Julien Peltier, Orsolya Bilkei-Gorzo, Matthias Trost
Methods in molecular biology (Clifton, N.J.) - 2017

A mass spectrometric-derived cell surface protein

atlas.

Damaris Bausch-Fluck, Andreas Hofmann, Thomas Bock, Andreas P Frei, Ferdinando Cerciello, Andrea Jacobs, Hansjoerg Moest, Ulrich Omasits, Rebekah L Gundry, Charles Yoon, Ralph Schiess, Alexander Schmidt, Paulina Mirkowska, Anetta Härtlova, Jennifer E Van Eyk, Jean-Pierre Bourquin, Ruedi Aebersold, Kenneth R Boheler, Peter Zandstra, Bernd Wollscheid
PloS one - 2015

High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived

macrophages.

Manman Guo, Anetta Härtlova, Brian D Dill, Alan R Prescott, Marek Gierliński, Matthias Trost
Proteomics - 2015

Quantitative proteome analysis of temporally resolved phagosomes following uptake via key phagocytic

receptors.

Brian D Dill, Marek Gierlinski, Anetta Härtlova, Alba González Arandilla, Manman Guo, Rosemary G Clarke, Matthias Trost
Molecular & cellular proteomics : MCP - 2015

Quantitative proteomics analysis of macrophage-derived lipid rafts reveals induction of autophagy pathway at the early time of Francisella tularensis LVS

infection.

Anetta Härtlova, Marek Link, Jana Balounova, Martina Benesova, Ulrike Resch, Adela Straskova, Margarita Sobol, Anatoly Philimonenko, Pavel Hozak, Zuzana Krocova, Nelson Gekara, Dominik Filipp, Jiri Stulik
Journal of proteome research - 2014

Application of SILAC labeling to primary bone marrow-derived dendritic cells reveals extensive GM-CSF-dependent arginine

metabolism.

Ivo Fabrik, Marek Link, Anetta Härtlova, Vera Dankova, Pavel Rehulka, Jiri Stulik
Journal of proteome research - 2014

Serving the new masters - dendritic cells as hosts for stealth intracellular

bacteria.

Ivo Fabrik, Anetta Härtlova, Pavel Rehulka, Jiri Stulik
Cellular microbiology - 2013

A proteomic view of the host-pathogen interaction: The host

perspective.

Anetta Härtlova, Zuzana Krocova, Lukas Cerveny, Jiri Stulik
Proteomics - 2011

Membrane rafts: a potential gateway for bacterial entry into host

cells.

Anetta Härtlova, Lukas Cerveny, Martin Hubalek, Zuzana Krocova, Jiri Stulik
Microbiology and immunology - 2010

Activation of B cell apoptotic pathways in the course of Francisella tularensis

infection.

Lucie Zivna, Zuzana Krocova, Anetta Härtlova, Klara Kubelkova, Jitka Zakova, Emil Rudolf, Roman Hrstka, Ales Macela, Jiri Stulik
Microbial pathogenesis - 2010

Interaction of B cells with intracellular pathogen Francisella

tularensis.

Zuzana Krocova, Anetta Härtlova, Dagmar Souckova, Lucie Zivna, Michal Kroca, Emil Rudolf, Ales Macela, Jiri Stulik
Microbial pathogenesis - 2008

Anetta Härtlova

Universitetslektor

Publikationer