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Lars Palmqvist research group

Acute myeloid leukemia – pathogenic mechanisms and clinical diagnostics

Lars Palmqvist

Contact Information | List of Publications

Acute myeloid leukemia (AML) is the most common form of acute leukemia and affects both children and adults. In children, this form of leukemia is associated with a much worse prognosis than the common form of childhood leukemia, acute lymphoblastic leukemia. Better understanding of the mechanisms behind this form of leukemia and improved treatment decisions are of outmost importance for the fighting of this disease.

The overall aim of our projects is to identify molecular mechanisms involved in the development of AML and novel ways of identifying and target leukemic cells in patients. Our clinical research is performed on samples from patients with acute myeloid leukemia, both children and adults. Pathogenic mechanisms for the development of this disease are studied in a murine bone marrow transplantation model. We also perform stem cell research on hematopoietic stem cells in human cord blood and mouse bone marrow. We believe that our investigations will lead to a better understanding of the development of malignant hematological disorders and to better risk stratification of patients with acute leukemia and ultimately to better treatment.

Additional information
PDF 1: Lars Palmqvist - Molecular mechanisms involved in the regulation of hematopoiesis and development of hematological disorders PDF 2: Linda Fogelstrand – Clinical studies on minimal residual disease detection in acute myeloid leukemia PDF 3: Lars Palmqvist – Defining hematopoietic stem cell content in human cord blood

Group members

Lars Palmqvist, MD, PhD, Associate Professor, group leader
Linda Fogelstrand, MD, PhD, Associate Professor,assistant group leader
Laleh Arabanian, PhD, post doc
Stella Wu, MD, PhD, post doc
Anna Staffas, PhD, post doc
Sofia Frändberg, MD, PhD student
Lene Karlsson, MD, PhD student
Erik Malmberg, MD, PhD student
Sofie Johansson Alm, research assistant
Sara Ståhlman, MSc
Carina Wasslavik, MSc
Tina Nilsson, MSc
Anders Östlund, medical student

Sidansvarig: Dan Baeckström|Sidan uppdaterades: 2015-11-27

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