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Research groups at Dept. of Microbiology and Immunology

Research is focused on infection and immunity at mucosal surfaces and includes studies on bacterial and viral pathogens that infect the gastrointestinal-, genital- and respiratory tracts. Research programs in the following areas are ongoing:
• Pathogenesis of infections caused by Vibrio cholera, ETEC, Helicobacter pylori, Salmonella, Influenza virus and herpes simplex virus
• Regulation of immune responses at mucosal surfaces
• Development of adjuvants to modulate immunity versus tolerance at mucosal surfaces
• Development of vaccines to V. cholera, ETEC, H. pylori, Influenza and Herpes virus
• Mechanisms underlying inflammatory bowel diseases, stomach cancer, colorectal cancer, allergy and autoimmune diseases such as diabetes
• The role of intestinal dendritic cells in immunity, tolerance and disease
• The biology of NKT cells, mast cells and intraepithelial lymphocytes
• Water-borne infections and epidemiology of infections

The department has many ongoing international collaborations with researchers in Europe, North and South America, Asia and Australia. Research projects are funded by national and international foundations including the Swedish Research Council, the Swedish Cancer Foundation, Vinnova, the European Union, the Juvenile Diabetes Foundation, PATH and the Gates Foundation. Projects use state of the art technology in flow cytometry, cell sorting, fluorescence microscopy, gene expression and genome sequencing.


Davide Angeletti
B cell and antibody immunodominance in antiviral immune responses

Mats Bemark
B cell activation and the germinal centre reaction

Susanna Cardell
Regulation of autoimmunity and tumor immunity

Ali M. Harandi
Novel mucosal adjuvants and female genital tract immunity

Jan Holmgren
Cholera toxin, mucosal immunity and mucosal vaccines | Gothenburg University Vaccine Research Centre (GUVAX)

Michael Lebens
Recombinant fusion proteins based on cholera toxin B subunit for the prevention and treatment of autoimmune disease

Nils Lycke
Mucosal immunoregulation and adjuvants

Thomas Nyström
Cellular Aging and Protein Quality Control

Marianne Quiding-Järbrink
Lymphocyte recruitment to gastrointestinal tissues

Sukanya Raghavan
Studies into mechanisms of immunity against Helicobacter pylori infection

Ann-Mari Svennerholm
Infection and immunity studies of ETEC and Helicobacter pylori | Gastrointestinal infections, water and health

Anetta Svitorka Härtlova
Molecular mechanisms of innate immune signaling

Åsa Torinsson Naluai
Molecular mechanisms involved in chronic inflammation

Mary Jo Wick
Intestinal dendritic cells in health and disease

Ulf Yrlid
Improvements of immune responses against colorectal cancers and enterotoxins

Lena Öhman
Gut microbiota, immune profile and the link to gastrointestinal diseases

Sidansvarig: Dan Baeckström|Sidan uppdaterades: 2018-11-06

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