Mats Bemark

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR

Marcus Borenäs, Ganesh Umapathy, Dan E. Lind, Wei-Yun Lai, Jikui Guan, Joel Johansson, Eva Jennische, Alexander Schmidt, Yeshwant Kurhe, Jonatan L. Gabre, Agata Aniszewska, Anneli Strömberg, Mats Bemark, Michael N. Hall, Jimmy Van den Eynden, Bengt Hallberg, Ruth H. Palmer
Proceedings of the National Academy of Sciences of the United States of America - 2024

Human intestinal B cells in inflammatory

diseases.

Jo Spencer, Mats Bemark
Nature reviews. Gastroenterology & hepatology - 2023

Longitudinal single-cell analysis of SARS-CoV-2-reactive B cells uncovers persistence of early-formed, antigen specific

clones.

Lydia Scharf, Hannes Axelsson, Aikaterini Emmanouilidi , Nimitha Rose Mathew, Daniel J Sheward, Susannah Leach, Pauline Isakson, Ilya Smirnov, Emelie Marklund, Nicolae Miron, Lars-Magnus Andersson, Magnus Gisslén, Ben Murrell, Anna Lundgren, Mats Bemark, Davide Angeletti
JCI insight - 2023

High Exposure to Perfluoroalkyl Substances and Antibody Responses to SARS-CoV-2 mRNA Vaccine-an Observational Study in Adults from Ronneby,

Sweden.

Axel G Andersson, Anna Lundgren, Yiyi Xu, Christel Nielsen, Christian H Lindh, Daniela Pineda, Julia Cederlund, Elisavet Pataridou, Sandra Søgaard Tøttenborg, Kajsa Ugelvig Petersen, Tony Fletcher, Martin Lagging, Mats Bemark, Kristina Jakobsson, Ying Li
Environmental health perspectives - 2023

Plasmablasts in previously immunologically naive COVID-19 patients express markers indicating mucosal homing and secrete antibodies cross-reacting with SARS-CoV-2 variants and other

beta-coronaviruses

Anna Lundgren, Susannah Leach, Hannes Axelsson, Pauline Isakson, Kristina Nyström, Lydia Scharf, Bengt A. Andersson, Nicolae Miron, Emelie Marklund, Lars-Magnus Andersson, Magnus Gisslén, Davide Angeletti, Mats Bemark
Clinical and Experimental Immunology - 2023

Defective peripheral B cell selection in common variable immune deficiency patients with autoimmune

manifestations.

Vanda Friman, Isabella Quinti, Alexey N Davydov, Mikhail Shugay, Chiara Farroni, Erik Engström, Shirin Pour Akaber, Sabina Barresi, Ahmed Mohamed, Federica Pulvirenti, Cinzia Milito, Guido Granata, Ezio Giorda, Sara Ahlström, Johanna Karlsson, Emiliano Marasco, Valentina Marcellini, Chiara Bocci, Simona Cascioli, Marco Scarsella, Ganesh Phad, Andreas Tilevik, Marco Tartaglia, Mats Bemark, Dmitriy M Chudakov, Rita Carsetti, Ola Grimsholm
Cell reports - 2023

Weller et al, T-independent responses to polysaccharides in humans mobilize marginal zone B cells pre-diversified against gut bacterial antigens

.

Jo Spencer, Thomas J Tull, Mats Bemark
Immunology letters - 2023

Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote

survival.

Kathrin Pfeifer, Georg Wolfstetter, Vimala Anthonydhason, Tafheem Masudi, Badrul Arefin, Mats Bemark, Patricia Mendoza-García, Ruth H. Palmer
Disease models & mechanisms - 2022

Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic

adaptation.

Adi Biram, Jingjing Liu, Hadas Hezroni, Natalia Davidzohn, Dominik Schmiedel, Eman Khatib-Massalha, Montaser Haddad, Amalie Grenov, Sacha Lebon, Tomer Meir Salame, Nili Dezorella, Dotan Hoffman, Paula Abou Karam, Moshe Biton, Tsvee Lapidot, Mats Bemark, Roi Avraham, Steffen Jung, Ziv Shulman
Immunity - 2022

IGF1R signalling is a guardian of self-tolerance restricting autoantibody

production.

Malin Erlandsson, Seval Erdogan, Caroline Wasén, Karin Andersson, Sofia Töyrä Silfverswärd, Rille Pullerits, Mats Bemark, Maria Bokarewa
Frontiers in immunology - 2022

Confirmed reinfection with SARS-CoV-2 during a pregnancy: A case

report.

Verena Sengpiel, Ylva Carlsson, Jan-Åke Liljeqvist, Anders Elfvin, Ing-Marie Fyhr, Anna Lundgren, Kristina Nyström, Mats Bemark, Magnus Gisslén, Johan Ringlander
Clinical case reports - 2022

Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and

blood.

Jacqueline H Y Siu, Michael J Pitcher, Thomas J Tull, Rebekah L Velounias, William Guesdon, Lucia Montorsi, Krishnaa T Mahbubani, Richard Ellis, Pawan Dhami, Katrina Todd, Ulrich D Kadolsky, Michelle Kleeman, David P D'Cruz, Kourosh Saeb-Parsy, Mats Bemark, Gavin J Pettigrew, Jo Spencer
Science immunology - 2022

Clonotypic analysis of protective influenza M2e-specific lung resident Th17 memory cells reveals extensive functional

diversity.

Ajibola Omokanye, Li Ching Ong, Cristina Lebrero-Fernandez, Valentina Bernasconi, Karin Schön, Anneli Stensson, Mats Bemark, Xavier Saelens, Paulo Czarnewski, Nils Y Lycke
Mucosal immunology - 2022

Longevity of anti-spike and anti-nucleocapsid antibodies after COVID-19 in solid organ transplant recipients compared to immunocompetent

controls.

John M. Söfteland, Magnus Gisslén, Jan-Åke Liljeqvist, Vanda Friman, Emily de Coursey, Kristjan Karason, Jan Ekelund, Marie Felldin, Jesper Magnusson, Seema Baid-Agrawal, Carin Wallquist, Andreas Schult, Hanna Jacobsson, Anders Bergdahl, Mats Bemark, Lars-Magnus Andersson, Inger Holm Gunnarsson, Jan Stenström, Susannah Leach
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 2022

Peyer's patch TH17 cells are dispensable for gut IgA responses to oral

immunization.

Inta Gribonika, Anneli Strömberg, Cristina Lebrero-Fernandez, Karin Schön, James Moon, Mats Bemark, Nils Y Lycke
Science immunology - 2022

DamID transcriptional profiling identifies the Snail/Scratch transcription factor Kahuli as an Alk target in the Drosophila visceral

mesoderm.

Patricia Mendoza, Swaraj Basu, Sanjay Sukumar, Badrul Arefin, Georg Wolfstetter, Vimala Anthonydhason, Linnea Molander, Ezgi Uçkun, Henrik Lindehell, Cristina Lebrero-Fernandez, Jan Larsson, Erik Larsson, Mats Bemark, Ruth H. Palmer
Development (Cambridge, England) - 2021

Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse

brain.

Aura Zelco, Vanja Börjesson , Jurrian K. de Kanter, Cristina Lebrero-Fernandez, Volker M. Lauschke, Eridan Rocha-Ferreira, Gisela M A Nilsson, Syam Nair, Pernilla Svedin, Mats Bemark, Henrik Hagberg, Carina Mallard, Frank C P Holstege, Xiaoyang Wang
Genes & development - 2021

Human marginal zone B cell development from early T2

progenitors.

Thomas J Tull, Michael J Pitcher, William Guesdon, Jacqueline H Y Siu, Cristina Lebrero-Fernandez, Yuan Zhao, Nedyalko Petrov, Susanne Heck, Richard Ellis, Pawan Dhami, Ulrich D Kadolsky, Michelle Kleeman, Yogesh Kamra, David J Fear, Susan John, Wayel Jassem, Richard W Groves, Jeremy D Sanderson, Michael D Robson, David P D'Cruz, Mats Bemark, Jo Spencer
The Journal of experimental medicine - 2021

A Model System for Feralizing Laboratory Mice in Large Farmyard-Like

Pens.

Henriette Arnesen, Linn Emilie Knutsen, Bente Wabakken Hognestad, Grethe Marie Johansen, Mats Bemark, Oliver Pabst, Anne Kristine Storset, Preben Boysen
Frontiers in microbiology - 2021

Know your enemy or find your friend?-Induction of IgA at mucosal

surfaces.

Mats Bemark, Davide Angeletti
Immunological reviews - 2021

Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B

cells.

Nimitha Rose Mathew, Jayalal Jayanthan, Ilya Smirnov, Jonathan L Robinson, Hannes Axelsson, Sravya Sowdamini Nakka, Aikaterini Emmanouilidi , Paulo Czarnewski, William T Yewdell, Karin Schön, Cristina Lebrero-Fernandez, Valentina Bernasconi, William Rodin, Ali M Harandi, Nils Y Lycke, Nicholas Borcherding, Jonathan W Yewdell, Victor Greiff, Mats Bemark, Davide Angeletti
Cell reports - 2021

Longitudinal Follow Up of Immune Responses to SARS-CoV-2 in Health Care Workers in Sweden With Several Different Commercial IgG-Assays, Measurement of Neutralizing Antibodies and CD4+ T-Cell

Responses.

Emelie Marklund, Susannah Leach, Kristina Nyström, Anna Lundgren, Jan-Åke Liljeqvist, Staffan Nilsson, Aylin Yilmaz, Lars-Magnus Andersson, Mats Bemark, Magnus Gisslén
Frontiers in immunology - 2021

B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's

Patches.

Adi Biram, Eitan Winter, Alice E Denton, Irina Zaretsky, Bareket Dassa, Mats Bemark, Michelle A Linterman, Gur Yaari, Ziv Shulman
Cell reports - 2020

Serum-IgG responses to SARS-CoV-2 after mild and severe COVID-19 infection and analysis of IgG

non-responders.

Emelie Marklund, Susannah Leach, Hannes Axelsson, Kristina Nyström, Helene Norder, Mats Bemark, Davide Angeletti, Anna Lundgren, Staffan Nilsson, Lars-Magnus Andersson, Aylin Yilmaz, Magnus Lindh, Jan-Åke Liljeqvist, Magnus Gisslén
PloS one - 2020

Class-switch recombination to IgA in the Peyer's patches requires natural thymus-derived Tregs and appears to be antigen

independent.

Inta Gribonika, Dubravka Grdic Eliasson, Rakesh Chandode, Karin Schön, Anneli Strömberg, Mats Bemark, Nils Y Lycke
Mucosal immunology - 2019

BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer's

patches.

Adi Biram, Anneli Strömberg, Eitan Winter, Liat Stoler-Barak, Ran Salomon, Yoseph Addadi, Rony Dahan, Gur Yaari, Mats Bemark, Ziv Shulman
Nature immunology - 2019

Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial

dome.

Rathan Komban, Anneli Strömberg, Adi Biram, Jakob Cervin, Cristina Lebrero-Fernandez, Neil Mabbott, Ulf Yrlid, Ziv Shulman, Mats Bemark, Nils Y Lycke
Nature communications - 2019

Global distribution of DNA hydroxymethylation and DNA methylation in chronic lymphocytic

leukemia.

Sara Wernig-Zorc, Mukesh Pratap Yadav, Pradeep Kumar Kopparapu, Mats Bemark, Hallgerdur Lind Kristjansdottir, Per-Ola Andersson, Chandrasekhar Kanduri, Meena Kanduri
Epigenetics & chromatin - 2019

Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma

cells.

Diana Lizeth Cervantes-Madrid, Joanna Szydzik, Marcus Borenäs, Mats Bemark, Jean Cui, Ruth H. Palmer, Bengt Hallberg
Scientific reports - 2019

Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid

tissue.

Yuan Zhao, Mohamed Uduman, Jacqueline H Y Siu, Thomas J Tull, Jeremy D Sanderson, Yu-Chang Bryan Wu, Julian Q Zhou, Nedyalko Petrov, Richard Ellis, Katrina Todd, Konstantia-Maria Chavele, William Guesdon, Anna Vossenkamper, Wayel Jassem, David P D'Cruz, David J Fear, Susan John, Dagmar Scheel-Toellner, Claire Hopkins, Estefania Moreno, Natalie L Woodman, Francesca Ciccarelli, Susanne Heck, Steven H Kleinstein, Mats Bemark, Jo Spencer
Nature communications - 2018

M2e-tetramer-specific memory CD4 T cells are broadly protective against influenza

infection.

Dubravka Grdic Eliasson, Ajibola Omokanye, Karin Schön, Ulf Alexander Wenzel, Valentina Bernasconi, Mats Bemark, A Kolpe, K El Bakkouri, T Ysenbaert, L Deng, W Fiers, X Saelens, Nils Y Lycke
Mucosal immunology - 2018

Determination of blood cell subtype concentrations from frozen whole blood samples using TruCount

beads

Cecilia Langenskiöld, Karin Mellgren, Jonas Abrahamsson, Mats Bemark
Cytometry Part B - Clinical Cytometry - 2018

Epstein-barr virus, but not cytomegalovirus, latency accelerates the decay of childhood measles and rubella vaccine responses-A 10-year follow-up of a Swedish birth

cohort

Gintare Lasaviciute, Sophia Björkander, Claudia Carvalho-Queiroz, Ida Hed Myrberg, Bianca Nussbaum, Caroline Nilsson, Mats Bemark, Anna Nilsson, Eva Sverremark-Ekström, Shanie Saghafian-Hedengren
Frontiers in Immunology - 2017

The regulation of gut mucosal IgA B-cell responses: recent

developments

Nils Y Lycke, Mats Bemark
Mucosal Immunology - 2017

Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral

immunization

Mats Bemark, H. Hazanov, Anneli Strömberg, Rathan Komban, Joel Holmqvist, Sofia Köster, Johan Mattsson, P. Sikora, R. Mehr, Nils Y Lycke
Nature Communications - 2016

The composition of the gut microbiota shapes the colon mucus

barrier.

Hedvig E Jakobsson, Ana María Rodríguez-Piñeiro, André Schütte, Anna Ermund, Preben Boysen, Mats Bemark, Felix Sommer, Fredrik Bäckhed, Gunnar C. Hansson, Malin E V Johansson
EMBO reports - 2015

Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch

recombination.

Mattias Svensson, Karin Andersson, Caroline Wasén, Malin Erlandsson, Merja Nurkkala Karlsson, Ing-Marie Jonsson, Mikael Brisslert, Mats Bemark, Maria Bokarewa
Proceedings of the National Academy of Sciences of the United States of America - 2015

Translating transitions - How to decipher peripheral human B cell

development

Mats Bemark
Journal of Biomedical Research - 2015

Mucosal B Cell Differentiation and

Regulation

Nils Y Lycke, Mats Bemark, J. Spencer
Mucosal Immunology: Fourth Edition. Volume 1 - 2015

The 18th Germinal Centre

Meeting.

Nils Y Lycke, Lill Mårtensson-Bopp, Ulf Yrlid, Mats Bemark
Scandinavian journal of immunology - 2014

A glycosylation-dependent CD45RB epitope defines previously unacknowledged CD27(-)IgM(high) B cell subpopulations enriched in young children and after hematopoietic stem cell

transplantation.

Mats Bemark, Linda Friskopp, Shanie Saghafian-Hedengren, Susanne Koethe, Anders Fasth, Jonas Abrahamsson, Eva Sverremark-Ekström, Bengt A. Andersson, Karin Mellgren
Clinical immunology (Orlando, Fla.) - 2013

Expression of the chemokine decoy receptor D6 is decreased in colon

adenocarcinomas.

Veronica Langenes, Helena Svensson, Lars Börjesson, Bengt Gustavsson, Mats Bemark, Åsa Sjöling, Marianne Quiding-Järbrink
Cancer immunology, immunotherapy : CII - 2013

Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA

responses.

Peter Bergqvist, Anneli Stensson, L Hazanov, Anna Holmberg, Johan Mattsson, R Mehr, Mats Bemark, Nils Y Lycke
Mucosal immunology - 2013

The role of Peyer's patches in synchronizing gut IgA

responses.

Nils Y Lycke, Mats Bemark
Frontiers in immunology - 2012

Induction of gut IgA production through T cell-dependent and T cell-independent

pathways.

Mats Bemark, Preben Boysen, Nils Y Lycke
Annals of the New York Academy of Sciences - 2012

Re-utilization of germinal centers in multiple PP results in highly synchronized, oligoclonal and affinity matured gut IgA

responses

Nils Y Lycke, Peter Bergqvist, Anneli Stensson, R. Mehr, Mats Bemark
Journal of Immunology - 2012

Translational Mini-Review Series on B cell subsets in disease. Reconstitution after haematopoietic stem cell transplantation - revelation of B cell developmental pathways and lineage

phenotypes.

Mats Bemark, Joel Holmqvist, Jonas Abrahamsson, Karin Mellgren
Clinical and experimental immunology - 2012

Pivotal Advance: CD45RB glycosylation is specifically regulated during human peripheral B cell

differentiation.

Susanne Koethe, Linda Zander, Sofia Köster, Adelaide Annan, Anders Ebenfelt, Jo Spencer, Mats Bemark
Journal of leukocyte biology - 2011

A Unique Role of the Cholera Toxin A1-DD Adjuvant for Long-Term Plasma and Memory B Cell

Development

Mats Bemark, Peter Bergqvist, Anneli Stensson, Anna Holmberg, Johan Mattsson, Nils Y Lycke
Journal of Immunology - 2011

Mucosal adjuvants and long-term memory development with special focus on CTA1-DD and other ADP-ribosylating

toxins.

Nils Y Lycke, Mats Bemark
Mucosal immunology - 2010

T cell-independent IgA class switch recombination is restricted to the GALT and occurs prior to manifest germinal center

formation

Peter Bergqvist, Anneli Stensson, Nils Y Lycke, Mats Bemark
Journal of Immunology - 2010

Identification of genes deregulated in a Burkitt´s lymphoma cell line when adapted

for

Linda Zander, Mats Bemark
Cell Proliferation - 2008

Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal

centers.

Peter Bergqvist, Eva Gärdby, Anneli Stensson, Mats Bemark, Nils Y Lycke
Journal of immunology (Baltimore, Md. : 1950) - 2006

REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen

(PCNA).

Xi Shen, Sohee Jun, Lindsey E O'Neal, Eiichiro Sonoda, Mats Bemark, Julian E Sale, Lei Li
The Journal of biological chemistry - 2006

De livsviktiga mutationerna - Darwin på

cellnivå.

Mats Bemark
Tidskriften Medikament - 2004

Immortalized mouse cell lines that lack a functional Rev3 gene are hypersensitive to UV irradiation and cisplatin

treatment.

Linda Zander, Mats Bemark
DNA repair - 2004

Mats Bemark

Forskare

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